Nuclei DNA Slide: A Novel Method to Measure Biological Effects of Radiation Damage

There are many methods that can be used to detect and quantify radiation based on DNA damage, such as using cells and microorganism as models, Cadet’s et al. [1] study indicated that ultraviolet radiation damaged cellular DNA. The models of cells also delivered dose-response and time-response relationship the increase of Single Strand Break (SSB) and Double Strand Break (DSB) lesions in the DNA molecule obtained in the in vitro radiations [2]. It is reported that purified DNA and T4 endonuclease V was used as a gold standard for detection on UV damage to DNA [3]. Purified DNA molecules has been extensively used to study radiation during the last decades , the results obtained from such in vitro experiments are consistent with those from radiation of cells and tissues [4-6].